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Implicating PARP and NAD+ depletion in type I diabetes

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Abstract

Mice deficient in the PARP DNA repair enzyme are refractory to toxin-induced death of pancreatic beta cells and do not become diabetic (pages 314–319).

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Authors and Affiliations

  1. Department of Biochemistry Albert Einstein College of Medicine, Bronx, 10461, New York, USA

    Maureen J. Charron

  2. Research Division Joslin Diabetes Center Harvard Medical School, Boston, 02215, Massachusetts, USA

    Susan Bonner-Weir

Authors
  1. Maureen J. Charron
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  2. Susan Bonner-Weir
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Charron, M., Bonner-Weir, S. Implicating PARP and NAD+ depletion in type I diabetes . Nat Med 5, 269–270 (1999). https://doi.org/10.1038/6479

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