Skip to main content
Log in

Neurobiology

A genetic cause of age-related decline

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Genetic variation in a neuropeptide signalling pathway regulates age-related declines in health in nematode worms. This discovery points to a mechanism that influences individual differences in ageing. See Article p.198

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Regulation of ageing-associated health declines.

Notes

  1. See all news & views

References

  1. International Human Genome Sequencing Consortium. Nature 409, 860–921 (2001).

  2. Venter, J. C. et al. Science 291, 1304–1351 (2001).

    Google Scholar 

  3. Yin, J.-A. et al. Nature 551, 198–203 (2017).

    Article  ADS  CAS  Google Scholar 

  4. Yin, J.-A., Liu, X.-J., Yuan, J., Jiang, J. & Cai, S.-Q. J. Neurosci. 34, 3947–3958 (2014).

    Article  Google Scholar 

  5. Bargmann, C. I. BioEssays 34, 458–465 (2012).

    Article  CAS  Google Scholar 

  6. Bendesky, A. et al. Nature 544, 434–439 (2017).

    Article  ADS  CAS  Google Scholar 

  7. de Bono, M. & Bargmann, C. I. Cell 94, 679–689 (1998).

    Article  CAS  Google Scholar 

  8. Lim, M. M. et al. Nature 429, 754–757 (2004).

    Article  ADS  CAS  Google Scholar 

  9. McGrath, P. T. Curr. Opin. Neurobiol. 23, 24–28 (2013).

    Article  CAS  Google Scholar 

  10. Araque, A. et al. Neuron 81, 728–739 (2014).

    Article  CAS  Google Scholar 

  11. Bäckman, L., Lindenberger, U., Li, S.-C. & Nyberg, L. Neurosci. Biobehav. Rev. 34, 670–677 (2010).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Patrick T. McGrath.

Related links

Related links

Related links in Nature Research

Ageing: A stretch in time

Ageing: When less is more

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

McGrath, P. A genetic cause of age-related decline. Nature 551, 179–180 (2017). https://doi.org/10.1038/551179a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/551179a

  • Springer Nature Limited

Navigation