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The inflammasome turns 15

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The discovery of the inflammasome protein complex in 2002 was a breakthrough in our understanding of how the immune system triggers inflammation. Now researchers are attempting to modulate its activity to treat disease.

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Figure 1: The inflammasome.

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Author information

Authors and Affiliations

  1. VIB-UGent Center for Inflammation Research, VIB, Ghent, B-9052, Belgium

    Mohamed Lamkanfi

  2. Department of Internal Medicine, Ghent University,

    Mohamed Lamkanfi

  3. Department of Physiological Chemistry, Genentech, South San Francisco, 94080, California, USA

    Vishva M. Dixit

Authors
  1. Mohamed Lamkanfi
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  2. Vishva M. Dixit
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Corresponding authors

Correspondence to Mohamed Lamkanfi or Vishva M. Dixit.

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Lamkanfi, M., Dixit, V. The inflammasome turns 15. Nature 548, 534–535 (2017). https://doi.org/10.1038/548534a

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