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Chemical biology

Protein modification in a trice

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Organometallic reagents have been developed that chemically modify proteins and peptides specifically at cysteine amino-acid residues — potentially offering a general route to making therapeutically useful compounds. See Letter p.687

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Figure 1: Site-selective reactions with proteins.

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Authors and Affiliations

  1. Heather Maynard is in the Department of Chemistry and Biochemistry and the California NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095, USA.,

    Heather Maynard

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  1. Heather Maynard
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Correspondence to Heather Maynard.

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Maynard, H. Protein modification in a trice. Nature 526, 646–647 (2015). https://doi.org/10.1038/526646b

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