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Regenerative biology

Neuregulin 1 makes heart muscle

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Three studies reveal that augmentation of a signalling pathway involving the growth factor neuregulin 1 and its receptor protein ERBB2 can promote the generation of muscle cells in zebrafish, mice and infant heart tissue.

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Figure 1: Mending a broken heart.

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Authors and Affiliations

  1. Katherine E. Yutzey is in the Division of Molecular Cardiovascular Biology, Cincinnati Children's Medical Center, Cincinnati, Ohio 45229, USA.,

    Katherine E. Yutzey

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  1. Katherine E. Yutzey
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Correspondence to Katherine E. Yutzey.

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Yutzey, K. Neuregulin 1 makes heart muscle. Nature 520, 445–446 (2015). https://doi.org/10.1038/520445a

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