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Organic synthesis

Better chemistry through radicals

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An iron catalyst has been developed that mediates bond formation between a wide range of alkene reactants, opening up short synthetic routes to compounds that were previously accessible only through arduous pathways. See Article p.343

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Figure 1: Iron-catalysed carbon–carbon bond formation with unprecedented functional-group tolerance.

References

  1. Lo, J. C., Gui, J., Yabe, Y., Pan, C.-M. & Baran, P. S. Nature 516, 343–348 (2014).

    Article  ADS  CAS  Google Scholar 

  2. de Meijere, A. & Diederich, F. (eds) Metal-Catalyzed Cross-Coupling Reactions 2nd edn (Wiley, 2004).

    Book  Google Scholar 

  3. Nakamura, E. et al. Org. React. 83, Ch. 1, 1–209 (2014).

    MathSciNet  CAS  Google Scholar 

  4. Kato, K. & Mukaiyama, T. Chem. Lett. 21, 1137–1140 (1992).

    Article  Google Scholar 

  5. Lo, J. C., Yabe, Y. & Baran, P. S. J. Am. Chem. Soc. 136, 1304–1307 (2014).

    Article  CAS  Google Scholar 

  6. Rowlands, G. J. Tetrahedron 65, 8603–8655 (2009).

    Article  CAS  Google Scholar 

  7. Rowlands, G. J. Tetrahedron 66, 1593–1636 (2010).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Steven L. Castle is in the Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602, USA.,

    Steven L. Castle

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  1. Steven L. Castle
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Correspondence to Steven L. Castle.

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Castle, S. Better chemistry through radicals. Nature 516, 332–333 (2014). https://doi.org/10.1038/516332a

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