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Neurodegeneration

Alzheimer's disease under strain

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Two studies of amyloid-β protein aggregates, which cause Alzheimer's disease, find that different conformations of the aggregates can define different strains of the disorder, drawing parallels with prion diseases.

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Figure 1: Information encoded in protein aggregates.

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Correspondence to Adriano Aguzzi.

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Aguzzi, A. Alzheimer's disease under strain. Nature 512, 32–34 (2014). https://doi.org/10.1038/512032a

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