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Immunology

To affinity and beyond

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Tracking B cells in germinal centres — hotspots of B-cell proliferation and mutation during an immune response — reveals that those cells presenting the most antigen on their surface are programmed to dominate. See Letter p.637

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Figure 1: Selection in the germinal centre.

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Authors and Affiliations

  1. and in the Department of Medical Biology, David M. Tarlinton is at the Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia, University of Melbourne, Parkville.,

    David M. Tarlinton

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  1. David M. Tarlinton
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Correspondence to David M. Tarlinton.

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Tarlinton, D. To affinity and beyond. Nature 509, 573–574 (2014). https://doi.org/10.1038/509573a

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