Skip to main content
SpringerLink
Log in

Policy: NIH to balance sex in cell and animal studies

  • Comment
  • Published:

From Nature

View current issue Submit your manuscript

Janine A. Clayton and Francis S. Collins unveil policies to ensure that preclinical research funded by the US National Institutes of Health considers females and males.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Zucker, I. & Beery, A. K. Nature 465, 690 (2010).

    Article  CAS  ADS  Google Scholar 

  2. Beery, A. K. & Zucker, I. Neurosci. Biobehav. Rev. 35, 565–572 (2011).

    Article  Google Scholar 

  3. Mogil, J. S. & Chanda, M. L. Pain 117, 1–5 (2005).

    Article  Google Scholar 

  4. Franconi, F., Brunelleschi, S., Steardo, L. & Cuomo, V. Pharmacol. Res. 55, 81–95 (2007).

    Article  CAS  Google Scholar 

  5. Collins, F. S. & Tabak, L. A. Nature 505, 612–613 (2014).

    Article  Google Scholar 

  6. Landis, S. C. et al. Nature 490, 187–191 (2012).

    Article  CAS  ADS  Google Scholar 

  7. Voskuhl, R. R. & Palaszynski, K. Neuroscientist 7, 258–270 (2001).

    Article  CAS  Google Scholar 

  8. Wisdom, A. J., Cao, Y., Itoh, N., Spence, R. D. & Voskuhl, R. R. J. Neurosci. Res. 91, 901–908 (2013).

    Article  CAS  Google Scholar 

  9. Du, S. et al. Proc. Natl Acad. Sci. USA 111, 2806–2811 (2014).

    Article  CAS  ADS  Google Scholar 

  10. Ebers, G. C. et al. Lancet 363, 1773–1774 (2004).

    Article  CAS  Google Scholar 

  11. Fox, H. C., Morgan, P. T. & Sinha, R. Neuropsychopharmacol. 39, 1527–1537 (2014).

    Article  CAS  Google Scholar 

  12. Prendergast, B. J., Onishi, K. G. & Zucker, I. Neurosci. Biobehav. Rev. 40, 1–5 (2014).

    Article  Google Scholar 

  13. Du, L., Bayir, H. & Lai, Y. et al. J. Biol. Chem. 279, 38563–38570 (2004).

    Article  CAS  Google Scholar 

  14. Becker, J. B. et al. Endocrinology 146, 1650–1673 (2005).

    Article  CAS  Google Scholar 

  15. Chen, X. et al. PLoS Genet. 8, e1002709 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Janine A. Clayton is director of the US National Institutes of Health Office of Research on Women's Health, and associate director for research on women's health, Bethesda, Maryland, USA.,

    Janine A. Clayton

  2. Francis S. Collins is director of the US National Institutes of Health, Bethesda, Maryland, USA.,

    Francis S. Collins

Authors
  1. Janine A. Clayton
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Francis S. Collins
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Janine A. Clayton.

Related links

Related links

Related links in Nature Research

Biology: Cell sex matters 2013-Jul-31

Sex bias in trials and treatment must end 2010-Jun-09

Pregnant women deserve better 2010-Jun-09

Putting gender on the agenda 2010-Jun-09

Males still dominate animal studies 2010-Jun-09

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Clayton, J., Collins, F. Policy: NIH to balance sex in cell and animal studies. Nature 509, 282–283 (2014). https://doi.org/10.1038/509282a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/509282a

  • Springer Nature Limited

This article is cited by

Search

Navigation