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Metabolism

Targeting a fat-accumulation gene

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An enzyme that links two metabolic hubs has been found to be upregulated in the fat cells of overweight mice. Inhibition of the gene encoding this enzyme protects mice from diet-induced obesity. See Letter p.258

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Figure 1: Accelerating fat-cell metabolism.

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Correspondence to Charles Brenner.

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Brenner, C. Targeting a fat-accumulation gene. Nature 508, 194–195 (2014). https://doi.org/10.1038/508194a

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