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A second layer of information in RNA

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Three studies have characterized the full complement of RNA folding in cells. They find large numbers of secondary structures in RNA, some of which may have functional consequences for the cell. See Letters p.696, p.701 & p.706

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Figure 1: Principles of RNA primary sequence and secondary structure.

References

  1. Crick, F. Nature 227, 561–563 (1970).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Ding, Y. et al. Nature 505, 696–700 (2014).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Rouskin, S., Zubradt, M., Washietl, S., Kellis, M. & Weissmann, J. S. Nature 505, 701–705 (2014).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Wan, Y. et al. Nature 505, 706–709 (2014).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  5. Woodson, S. A. Curr. Opin. Chem. Biol. 12, 667–673 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Dominski, Z. & Marzluff, W. F. Gene 396, 373–390 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Halvorsen, M., Martin, J. S., Broadaway, S. & Laederach, A. PLoS Genet. 6, e1001074 (2010).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Tijerina, P., Mohr, S. & Russell, R. Nature Protocols 2, 2608–2623 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Shcherbakova, I., Mitra, S., Laederach, A. & Brenowitz, M. Curr. Opin. Chem. Biol. 12, 655–666 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Martin, J. S. et al. RNA 18, 77–87 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Tucker, B. J. & Breaker, R. R. Curr. Opin. Struct. Biol. 15, 342–348 (2005).

    Article  CAS  PubMed  Google Scholar 

  12. Ulitsky, I. & Bartel, D. P. Cell 154, 26–46 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Silvia B. V. Ramos and Alain Laederach are in the Obstetrics and Gynecology Department and the Biology Department, University of North Carolina, Chapel Hill, North Carolina 27599-3280, USA.,

    Silvia B. V. Ramos & Alain Laederach

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  1. Silvia B. V. Ramos
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  2. Alain Laederach
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Correspondence to Silvia B. V. Ramos or Alain Laederach.

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Ramos, S., Laederach, A. A second layer of information in RNA. Nature 505, 621–622 (2014). https://doi.org/10.1038/505621a

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