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Stem cells

Sex specificity in the blood

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Haematopoietic stem cells, from which blood cells originate, are shown to respond to oestrogen and divide more frequently in female mice than in males, probably preparing females for the increased demand for blood in pregnancy. See Letter p.555

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Figure 1: Oestrogen regulates stem-cell cycling.

References

  1. Nakada, D., Levi, B. P. & Morrison, S. J. Neuron 70, 703–718 (2011).

    Article  CAS  Google Scholar 

  2. Shingo, T. et al. Science 299, 117–120 (2003).

    Article  ADS  CAS  Google Scholar 

  3. Ray, R. et al. Mol. Med. 14, 493–501 (2008).

    Article  CAS  Google Scholar 

  4. Deasy, B. M. et al. J. Cell Biol. 177, 73–86 (2007).

    Article  CAS  Google Scholar 

  5. Nakada, D. et al. Nature 505, 555–558 (2014).

    Article  ADS  CAS  Google Scholar 

  6. Illing, A. et al. Haematologica 97, 1131–1135 (2012).

    Article  CAS  Google Scholar 

  7. Orford, K. W. & Scadden, D. T. Nature Rev. Genet. 9, 115–128 (2008).

    Article  CAS  Google Scholar 

  8. Mandal, P. K., Blanpain, C. & Rossi, D. J. Nature Rev. Mol. Cell Biol. 12, 198–202 (2011).

    Article  CAS  Google Scholar 

  9. Mohrin, M. et al. Cell Stem Cell 7, 174–185 (2010).

    Article  CAS  Google Scholar 

  10. Nielsen, J. H., Svensson, C., Galsgaard, E. D., Møldrup, A. & Billestrup, N. J. Mol. Med. 77, 62–66 (1999).

    Article  CAS  Google Scholar 

  11. Notta, F., Doulatov, S. & Dick, J. E. Blood 115, 3704–3707 (2010).

    Article  CAS  Google Scholar 

  12. Baerlocher, G. M. et al. Blood 114, 219–222 (2009).

    Article  CAS  Google Scholar 

  13. Jain, A. & Naniwadekar, M. BMC Hematol. 13, 10 (2013).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Dena S. Leeman and Anne Brunet are in the Department of Genetics, the Cancer Biology Program, and the Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, California 94305, USA.,

    Dena S. Leeman & Anne Brunet

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  1. Dena S. Leeman
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  2. Anne Brunet
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Correspondence to Anne Brunet.

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Leeman, D., Brunet, A. Sex specificity in the blood. Nature 505, 488–489 (2014). https://doi.org/10.1038/505488a

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