A rare gene variant has been found that decreases the peptide deposition seen in the brains of people with Alzheimer's disease. The mutation may also slow the normal cognitive decline that occurs with age. See Letter p.96
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B.D.S. is a consultant for Janssen Pharmaceutica, Beerse; Envivo Pharmaceuticals, Boston; and Remynd NV, Leuven. He also receives research funding from Janssen Pharmaceutica, Beerse.
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De Strooper, B., Voet, T. A protective mutation. Nature 488, 38–39 (2012). https://doi.org/10.1038/488038a
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DOI: https://doi.org/10.1038/488038a
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