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Regenerative medicine

Reprogramming the injured heart

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When the heart is injured, the muscle does not regenerate and scars are produced. This process can be attenuated in the hearts of live mice by forcing scar-forming cells to become muscle cells. See Articles p.593 & p.599

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References

  1. Qian, L. et al. Nature 485, 593–598 (2012).

    Article  ADS  CAS  Google Scholar 

  2. Song, K. et al. Nature 485, 599–604 (2012).

    Article  ADS  CAS  Google Scholar 

  3. Davis, R. L., Weintraub, H. & Lassar, A. B. Cell 51, 987–1000 (1987).

    Article  CAS  Google Scholar 

  4. Murry, C. E., Kay, M. A., Bartosek, T., Hauschka, S. D. & Schwartz, S. M. J. Clin. Invest. 98, 2209–2217 (1996).

    Article  CAS  Google Scholar 

  5. Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    Article  CAS  Google Scholar 

  6. Ieda, M. et al. Cell 142, 375–386 (2010).

    Article  CAS  Google Scholar 

  7. Pang, Z. P. et al. Nature 476, 220–223 (2011).

    Article  ADS  CAS  Google Scholar 

  8. Vierbuchen, T. et al. Nature 463, 1035–1041 (2010).

    Article  ADS  CAS  Google Scholar 

  9. Szabo, E. et al. Nature 468, 521–526 (2010).

    Article  ADS  CAS  Google Scholar 

  10. Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. & Melton, D. A. Nature 455, 627–632 (2008).

    Article  ADS  CAS  Google Scholar 

  11. Sen, K. et al. Am. J. Pathol. 179, 1756–1767 (2011).

    Article  CAS  Google Scholar 

  12. Cheng, J., Wang, Y., Liang, A., Jia, L. & Du, J. Circ. Res. 110, 230–240 (2012).

    Article  CAS  Google Scholar 

  13. Laflamme, M. A. & Murry, C. E. Nature 473, 326–335 (2011).

    Article  ADS  CAS  Google Scholar 

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Correspondence to Charles E. Murry.

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Palpant, N., Murry, C. Reprogramming the injured heart. Nature 485, 585–586 (2012). https://doi.org/10.1038/485585a

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