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Fish heads and human disease

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The expression level of a single gene can determine head size in zebrafish, mirroring a human anatomical feature associated with neurological disorders such as autism and schizophrenia. See Letter p.363

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Figure 1: A gene for head size.

References

  1. Malhotra, D. & Sebat, J. Cell 148, 1223–1241 (2012).

    Article  CAS  Google Scholar 

  2. Cooper, G. M. et al. Nature Genet. 43, 838–846 (2011).

    Article  CAS  Google Scholar 

  3. Kaminsky, E. B. et al. Genet. Med. 13, 777–784 (2011).

    Article  Google Scholar 

  4. Golzio, C. et al. Nature 485, 363–367 (2012).

    Article  ADS  CAS  Google Scholar 

  5. Bochukova, E. G. et al. Nature 463, 666–670 (2010).

    Article  ADS  CAS  Google Scholar 

  6. Walters, R. G. et al. Nature 463, 671–675 (2010).

    Article  ADS  CAS  Google Scholar 

  7. Shinawi, M. et al. J. Med. Genet. 47, 332–341 (2010).

    Article  CAS  Google Scholar 

  8. McCarthy, S. E. et al. Nature Genet. 41, 1223–1227 (2009).

    Article  CAS  Google Scholar 

  9. Jacquemont, S. et al. Nature 478, 97–102 (2011).

    Article  ADS  CAS  Google Scholar 

  10. Weiss, L. A. et al. N. Engl. J. Med. 358, 667–675 (2008).

    Article  CAS  Google Scholar 

  11. Horev, G. et al. Proc. Natl Acad. Sci. USA 108, 17076–17081 (2011).

    Article  ADS  Google Scholar 

  12. Crepel, A. et al. Am. J. Med. Genet. B 156, 243–245 (2011).

    Article  Google Scholar 

  13. He, H., Tan, C. K., Downey, K. M. & So, A. G. Proc. Natl Acad. Sci. USA 98, 11979–11984 (2001).

    Article  ADS  CAS  Google Scholar 

  14. Scheffer, G. L. et al. Nature Med. 1, 578–582 (1995).

    Article  CAS  Google Scholar 

  15. Zhang, W. & Liu, H. T. Cell Res. 12, 9–18 (2002).

    Article  CAS  Google Scholar 

  16. Cohen, M. M. Jr Am. J. Med. Genet. C 117, 49–56 (2003).

    Article  Google Scholar 

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Correspondence to Jonathan Sebat.

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Malhotra, D., Sebat, J. Fish heads and human disease. Nature 485, 318–319 (2012). https://doi.org/10.1038/485318a

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