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Biochemistry

Favouring the unfavoured

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The naturally occurring antibiotic lasalocid A contains a chemical structure that is not expected to form readily. The enzyme that catalyses the formation of this structure has been identified, and its activity is a revelation. See Letter p.355

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Figure 1: Polyether antibiotics.

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Authors and Affiliations

  1. David E. Cane is in the Department of Chemistry, Brown University, Providence, Rhode Island 02912-9108, USA.,

    David E. Cane

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  1. David E. Cane
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Correspondence to David E. Cane.

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Cane, D. Favouring the unfavoured. Nature 483, 285–286 (2012). https://doi.org/10.1038/483285a

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