For more than 20 years, Brian Kobilka worked to create a portrait of a key cell receptor. Sometimes, the slow, steady approach wins.
This is a preview of subscription content, log in via an institution to check access.
References
Rasmussen, S. G. F et al. Nature 450, 383-387 (2007).
Rosenbaum, D. M. et al. Science 318, 1266-1273 (2007).
Cherezov, V. et al. Science 318, 1258-1265 (2007).
Rasmussen, S. G. F. et al. Nature 469, 175-180 (2011).
Rasmussen, S. G. F. et al. Nature http://dx.doi.org/10.1038/nature10361 (2011).
Dixon, R. A. F. et al. Nature 321, 75-79 (1986).
Ghanouni, P. et al. J. Biol. Chem. 276, 24433-24436 (2001).
Palczewski, K. et al. Science 289, 739-745 (2000).
Additional information
Lizzie Buchen is a freelance writer based in San Francisco, California.
Related links
Rights and permissions
About this article
Cite this article
Buchen, L. Cell signalling: It's all about the structure. Nature 476, 387–390 (2011). https://doi.org/10.1038/476387a
Published:
Issue Date:
DOI: https://doi.org/10.1038/476387a
- Springer Nature Limited
This article is cited by
-
Nobel work boosts drug development
Nature (2012)
-
Opioid receptors revealed
Nature (2012)