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Stem cells

Orphan receptors find a home

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The protein Lgr5 has been valuable as the undisputed marker of intestinal and other stem cells. It emerges that Lgr5 and its relatives also have essential signalling roles of relevance to health and disease. See Article p.293

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Figure 1: Cooperative signalling within stem cells.

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  1. Walter Birchmeier is at the Max Delbrück Center for Molecular Medicine, 13125 Berlin-Buch, Germany.,

    Walter Birchmeier

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  1. Walter Birchmeier
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Correspondence to Walter Birchmeier.

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Birchmeier, W. Orphan receptors find a home. Nature 476, 287–288 (2011). https://doi.org/10.1038/476287a

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