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Cell signalling

Why fasting worms age slowly

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Lipids of the N-acylethanolamine family mediate cell signalling across a wide range of organisms. In nematode worms, they translate food availability into fundamental choices about development that affect lifespan. See Letter p.226

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Figure 1: N-Acylethanolamines, feeding behaviour and lifespan.

FROM BOTTOM: K. WOTHE/MINDEN PICTURES/FLPA; S. STAMMERS/SPL; K. TELNES/IMAGEQUESTMARINE.COM; G. LACZ/FLPA; REINHARD/ARCO/NATUREPLCOM

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Authors and Affiliations

  1. Luciano De Petrocellis and Vincenzo Di Marzo are in the Endocannabinoid Research Group, Institute of Biomolecular Chemistry and Institute of Cybernetics, Consiglio Nazionale delle Ricerche, Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.,

    Luciano De Petrocellis & Vincenzo Di Marzo

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  1. Luciano De Petrocellis
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  2. Vincenzo Di Marzo
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Correspondence to Vincenzo Di Marzo.

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De Petrocellis, L., Di Marzo, V. Why fasting worms age slowly. Nature 473, 161–162 (2011). https://doi.org/10.1038/473161a

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