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Macrophages limit chemotherapy

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A major hurdle to successful cancer treatment is tumour resistance to chemotherapy. White blood cells called macrophages often infiltrate tumours in large numbers, and now appear to promote tumour chemoresistance.

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Figure 1: Macrophages promote tumour chemoresistance.

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Authors and Affiliations

  1. Michele De Palma is at the Angiogenesis and Tumour Targeting Research Unit, and HSR-TIGET, San Raffaele Scientific Institute, 20132-Milan, Italy.,

    Michele De Palma

  2. Department of Oncology, Claire E. Lewis is at the Academic Unit of Tumour Inflammation & Tumour Targeting, University of Sheffield Medical School, Sheffield S10 2RX, UK.,

    Claire E. Lewis

Authors
  1. Michele De Palma
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  2. Claire E. Lewis
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Correspondence to Michele De Palma or Claire E. Lewis.

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De Palma, M., Lewis, C. Macrophages limit chemotherapy. Nature 472, 303–304 (2011). https://doi.org/10.1038/472303a

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