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Molecular genetics

The sound of silence

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There are various ways in which apparently 'silent' DNA mutations — those that don't result in a change in the encoded protein — have untoward consequences. A striking example has emerged in a study of Crohn's disease.

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Authors and Affiliations

  1. Laurence D. Hurst is in the Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.,

    Laurence D. Hurst

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  1. Laurence D. Hurst
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Correspondence to Laurence D. Hurst.

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Hurst, L. The sound of silence. Nature 471, 582–583 (2011). https://doi.org/10.1038/471582a

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