Skip to main content
Log in

Reproductive biology

In vitro sperm maturation

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Anticancer therapies can impair male fertility. Whereas men can opt to freeze their sperm before treatment, young boys don't produce mature sperm and so lack this choice. Work in mice offers hope for such patients. See Letter p.504

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Possible scenario for preserving fertility, based on the new work1.

References

  1. Sato, T. et al. Nature 471, 504–507 (2011).

    Article  ADS  CAS  Google Scholar 

  2. Russell, L. D., Ettlin, R. A., Hikim, A. P. S. & Clegg, E. D. Histological and Histopathological Evaluation of the Testis (Cache River Press, 1990).

    Google Scholar 

  3. Staub, C. J. Androl. 22, 911–926 (2001).

    Article  CAS  Google Scholar 

  4. Gohbara, A. et al. Biol. Reprod. 83, 261–267 (2010).

    Article  CAS  Google Scholar 

  5. Price, P. J., Goldsborough, M. D. & Tilkins, M. L. International patent application: PCT/US98/00467 (1998).

  6. Brinster, R. L. & Zimmermann, J. W. Proc. Natl Acad. Sci. USA 91, 11298–11302 (1994).

    Article  ADS  CAS  Google Scholar 

  7. Kee, K., Angeles, V. T., Flores, M., Nguyen, H. N. & Reijo Pera, R. A. Nature 462, 222–225 (2009).

    Article  ADS  CAS  Google Scholar 

  8. Nayernia, K. et al. Dev. Cell 11, 125–132 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Marco Seandel or Shahin Rafii.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Seandel, M., Rafii, S. In vitro sperm maturation. Nature 471, 453–454 (2011). https://doi.org/10.1038/471453a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/471453a

  • Springer Nature Limited

Navigation