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Prion diseases

Infectivity versus toxicity

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Prions are infectious proteins that can cause deadly diseases in mammals. Detailed measurements of infectivity suggest that there may be distinct infectious and toxic versions of this protein. See Letter p.540

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Figure 1: Does PrP protein concentration matter?

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Authors and Affiliations

  1. Reed B. Wickner is in the Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0830, USA.,

    Reed B. Wickner

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  1. Reed B. Wickner
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Correspondence to Reed B. Wickner.

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Wickner, R. Infectivity versus toxicity. Nature 470, 470–471 (2011). https://doi.org/10.1038/470470a

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