With age comes wisdom, or so they say. The reality is that, with age, the ability to store memories declines. One way of tackling this problem might be to raise neuronal levels of the signalling molecule EphB2. See Article p.47
References
Cissé, M. et al. Nature 469, 47–52 (2011).
Tanzi, R. E. & Bertram, L. Cell 120, 545–555 (2005).
Walsh, D. M. & Selkoe, D. J. Neuron 44, 181–193 (2004).
Jack, C. R. Jr et al. Brain 133, 3336–3348 (2010).
Malenka, R. C. & Bear, M. F. Neuron 44, 5–21 (2004).
Kamenetz, F. et al. Neuron 37, 925–937 (2003).
Snyder, E. M. et al. Nature Neurosci. 8, 1051–1058 (2005).
Dalva, M. B. et al. Cell 103, 945–956 (2000).
Henderson, J. T. et al. Neuron 32, 1041–1056 (2001).
Grunwald, I. C. et al. Neuron 32, 1027–1040 (2001).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Malenka, R., Malinow, R. Recollection of lost memories. Nature 469, 44–45 (2011). https://doi.org/10.1038/469044a
Published:
Issue Date:
DOI: https://doi.org/10.1038/469044a
- Springer Nature Limited
This article is cited by
-
Role of BACE1 in Alzheimer’s synaptic function
Translational Neurodegeneration (2017)
-
Oligodendrocyte N-Methyl-d-aspartate Receptor Signaling: Insights into Its Functions
Molecular Neurobiology (2013)
-
PathNet: a tool for pathway analysis using topological information
Source Code for Biology and Medicine (2012)