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Cancer

Chemotherapy counteracted

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Resistance of tumour cells to chemotherapy can severely affect the efficacy of this anticancer treatment. The non-tumour cells of the organ in which the tumour resides may aid the emergence of such resistance.

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Figure 1: Endothelial stress response and chemoresistance.

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Authors and Affiliations

  1. Urban Emmenegger and Robert S. Kerbel are at the Sunnybrook Research Institute and Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada. They are also at the University of Toronto.,

    Urban Emmenegger & Robert S. Kerbel

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  1. Urban Emmenegger
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  2. Robert S. Kerbel
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Competing interests

R.S.K. is a consultant to Taiho and GSK Pharmaceuticals for metronomic chemotherapy, and is a recipient of sponsored research agreements from Pfizer and GSK to study small-molecule antiangiogenic receptor tyrosine kinase antagonists.

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Emmenegger, U., Kerbel, R. Chemotherapy counteracted. Nature 468, 637–638 (2010). https://doi.org/10.1038/468637a

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