Skip to main content
Log in

Reproductive ageing

Of worms and women

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

In roundworms, age-related decline in egg quality is regulated by specific humoral signalling pathways. If similar mechanisms operate in mammals, these findings may suggest ways to delay reproductive ageing in women.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Neuroendocrine regulation of reproductive ageing1.

References

  1. Luo, S., Kleemann, G. A., Ashraf, J. M., Shaw, W. M. & Murphy, C. T. Cell 143, 299–312 (2010).

    Article  CAS  Google Scholar 

  2. Hughes, S. E., Evason, K., Xiong, C. & Kornfeld, K. PLoS Genet. 3, e25 (2007).

    Article  Google Scholar 

  3. Luo, S., Shaw, W. M., Ashraf, J. & Murphy C. T. PLoS Genet. 5, e1000789 (2009).

    Article  Google Scholar 

  4. te Velde, E. R. & Pearson, P. L. Hum. Reprod. Update 8, 141–154 (2002).

    Article  Google Scholar 

  5. Downs, J. L. & Wise, P. M. Mol. Cell. Endocrinol. 299, 32–38 (2009).

    Article  CAS  Google Scholar 

  6. Meredith, S., Dudenhoeffer, G., Butcher, R. L., Lerner, S. P. & Walls, T. Biol. Reprod. 47, 162–168 (1992).

    Article  CAS  Google Scholar 

  7. Slot, K. A. et al. Reproduction 131, 525–532 (2006).

    Article  CAS  Google Scholar 

  8. Tatar, M. Ann. NY Acad. Sci. 1204, 149–155 (2010).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Flurkey, K., Harrison, D. Of worms and women. Nature 468, 386–387 (2010). https://doi.org/10.1038/468386a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/468386a

  • Springer Nature Limited

This article is cited by

Navigation