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Metabolism

Host and microbes in a pickle

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An Addendum to this article was published on 05 May 2010

Metabolic disorders such as obesity are characterized by long-term, low-grade inflammation. Under certain conditions, the resident microorganisms of the gut might contribute to this inflammation, resulting in disease.

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Figure 1: Host–microbe communication in systemic inflammation.

References

  1. Cornier, M. A. et al. Endocr. Rev. 29, 777–822 (2008).

  2. Vijay-Kumar, M. et al. Science 328, 228–231 (2010).

    Article  ADS  CAS  Google Scholar 

  3. Garrett, W. S., Gordon, J. I. & Glimcher, L. H. Cell 140, 859–870 (2010).

    Article  CAS  Google Scholar 

  4. Mazmanian, S. K., Round, J. L. & Kasper, D. L. Nature 453, 620–625 (2008).

    Article  ADS  CAS  Google Scholar 

  5. Wen, L. et al. Nature 455, 1109–1113 (2008).

    Article  ADS  CAS  Google Scholar 

  6. Turnbaugh, P. J. et al. Nature 444, 1027–1031 (2006).

    Article  ADS  Google Scholar 

  7. Cani, P. D. et al. Diabetes 56, 1761–1772 (2007).

    Article  CAS  Google Scholar 

  8. Hotamisligil, G. S. Cell 140, 900–917 (2010).

    Article  CAS  Google Scholar 

  9. Maslowski, K. M. et al. Nature 461, 1282–1286 (2009).

    Article  ADS  CAS  Google Scholar 

  10. Clarke, T. B. et al. Nature Med. 16, 228–231 (2010).

    Article  CAS  Google Scholar 

  11. Shi, H. et al. J. Clin. Invest. 116, 3015–3025 (2006).

    Article  CAS  Google Scholar 

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Gökhan Hotamisligil is on the scientific advisory board, is a shareholder and receives research support from Syndexa Pharmaceuticals.

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Li, P., Hotamisligil, G. Host and microbes in a pickle. Nature 464, 1287–1288 (2010). https://doi.org/10.1038/4641287a

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