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How cilia beat

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Physics provides new approaches to difficult biological problems: a plausible mathematical model of how cilia and flagella beat has been formulated, but it needs to be subjected to rigorous experimental tests.

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Figure 1: Axoneme structure and dynein regulation.
Figure 2: Self-organized oscillations in a system of opposed motors and springs.

References

  1. Camalet, S., Jülicher, F. & Prost, J. Phys. Rev. Lett. 82, 1590–1593 (1999).

    Article  ADS  CAS  Google Scholar 

  2. Riedel-Kruse, I. H., Hilfinger, A., Howard, J. & Jülicher, F. HFSP J. 1, 192–208 (2007).

    Article  Google Scholar 

  3. Hilfinger, A., Chattopadhyay, A. K. & Jülicher, F. Phys. Rev. E 79, 051918 (2009).

    Article  ADS  Google Scholar 

  4. Gibbons, I. R. & Rowe, A. J. Science 149, 424–426 (1965).

    Article  ADS  CAS  Google Scholar 

  5. Numata, N. et al. Biochem. Soc. Trans. 36, 131–135 (2008).

    Article  CAS  Google Scholar 

  6. Summers, K. E. & Gibbons, I. R. Proc. Natl Acad. Sci. USA 68, 3092–3096 (1971).

    Article  ADS  CAS  Google Scholar 

  7. Brokaw, C. J. Cell Motil. Cytoskel. 66, 425–436 (2009).

    Article  CAS  Google Scholar 

  8. Brokaw, C. J. Proc. Natl Acad. Sci. USA 72, 3102–3106 (1975).

    Article  ADS  CAS  Google Scholar 

  9. Schnitzer, M. J., Visscher, K. & Block, S. M. Nature Cell Biol. 2, 718–723 (2000).

    Article  CAS  Google Scholar 

  10. Vernon, G. G. & Woolley, D. M. Biophys. J. 87, 3934–3944 (2004).

    Article  CAS  Google Scholar 

  11. Fliegauf, M., Benzing, T. & Omran, H. Nature Rev. Mol. Cell Biol. 8, 880–893 (2007).

    Article  CAS  Google Scholar 

  12. Castleman, V. H. et al. Am. J. Hum. Genet. 84, 197–209 (2009).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. T. J. Mitchison is in the Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. timothy_mitchison@hms.harvard.edu,

    T. J. Mitchison

  2. H. M. Mitchison is at the Institute of Child Health, University College London, London WC1N 1EH, UK. h.mitchison@ich.ucl.ac.uk ,

    H. M. Mitchison

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  1. T. J. Mitchison
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  2. H. M. Mitchison
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Mitchison, T., Mitchison, H. How cilia beat. Nature 463, 308–309 (2010). https://doi.org/10.1038/463308a

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