What is the first signal that directs the rapid influx of immune cells to a wound to stave off potential infection? A study in the zebrafish reveals an unusual but well-qualified candidate.
References
Stramer, B. M., Mori, R. & Martin, P. J. Invest. Dermatol. 127, 1009–1017 (2007).
Niethammer, P., Grabher, C., Look, A. T. & Mitchison, T. J. Nature 459, 996–999 (2009).
Vestweber, D. Immunol. Rev. 218, 178–196 (2007).
Cvejic, A. et al. J. Cell Sci. 121, 3196–3206 (2008).
Kim, M.-H. et al. J. Invest. Dermatol. 128, 1812–1820 (2008).
Linden, J. Science 314, 1689–1690 (2006).
Shi, Y., Evans, J. E. & Rock, K. L. Nature 425, 516–521 (2003).
Scaffidi, P., Misteli, T. & Bianchi, M. E. Nature 418, 191–195 (2002).
McNeil, P. L. & Ito, S. J. Cell Sci. 96, 549–556 (1990).
Mathias, J. R. et al. J. Leukocyte Biol. 80, 1281–1288 (2006).
Renshaw, S. A. et al. Blood 108, 3976–3978 (2006).
Hall, C. et al. BMC Dev. Biol. 7, 42 (2007).
Schäfer, M. & Werner, S. Pharmacol. Res. 58, 165–171 (2008).
Lee, S.-R. et al. J. Biol. Chem. 277, 20336–20342 (2002).
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Martin, P., Feng, Y. Wound healing in zebrafish. Nature 459, 921–923 (2009). https://doi.org/10.1038/459921a
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DOI: https://doi.org/10.1038/459921a
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