Skip to main content
SpringerLink
Log in

Circadian clocks

Tips from the tip of the iceberg

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Daily remodelling of histone proteins underlies interactions between circadian clock genes and metabolic genes. This regulatory mechanism could be widespread, affecting other physiological processes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Clock genes in health and disease.

References

  1. Alenghat, T. et al. Nature 456, 997–1000 (2008).

    Article  ADS  CAS  Google Scholar 

  2. Takahashi, J., Turek, F. & Moore, R. (eds) Handbook of Behavioural Neurobiology Vol. 12 (Kluwer Academic/Plenum, 2001).

    Book  Google Scholar 

  3. Panda, S. et al. Cell 109, 307–320 (2002).

    Article  CAS  Google Scholar 

  4. Turek, F. et al. Science 308, 1043–1045 (2005).

    Article  ADS  CAS  Google Scholar 

  5. Preitner, N. et al. Cell 110, 251–260 (2002).

    Article  CAS  Google Scholar 

  6. Ripperger, J. & Schibler, U. Nature Genet. 38, 369–374 (2006).

    Article  CAS  Google Scholar 

  7. Doi, M., Hirayama, J. & Sassone-Corsi, P. Cell 125, 497–508 (2006).

    Article  CAS  Google Scholar 

  8. Etchegaray, J. et al. Nature 421, 177–182 (2003).

    Article  ADS  CAS  Google Scholar 

  9. Ramsey, K. et al. Annu. Rev. Nutr. 27, 219–240 (2007).

    Article  CAS  Google Scholar 

  10. Naylor, E. et al. J. Neurosci. 20, 8138–8143 (2000).

    Article  CAS  Google Scholar 

  11. McClung, C. A. Pharmacol. Ther. 114, 222–232 (2007).

    Article  CAS  Google Scholar 

  12. Renthal, W. & Nestler, E. J. Trends Mol. Med. 14, 341–350 (2008).

    Article  CAS  Google Scholar 

  13. Sharma, R. Schizophr. Res. 72, 79–90 (2005).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Fred W. Turek is at the Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois 60208–3520, USA. fturek@northwestern.edu ,

    Fred W. Turek

Authors
  1. Fred W. Turek
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The author has been a consultant and has received an honorarium and/or grant support from the following companies with an interest in sleep/circadian rhythms: Merck; Astra-Zeneca; Servier; Sanofi-Aventis, Resporonics; and Johnson & Johnson. He is also chief executive of (and holds equity in) a small company, NuNetix Inc., that works with pharmaceutical companies to test their compounds for effects on sleep and/or circadian rhythms.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Turek, F. Tips from the tip of the iceberg. Nature 456, 881–883 (2008). https://doi.org/10.1038/456881a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/456881a

  • Springer Nature Limited

This article is cited by

Search

Navigation