When the myelin layer that covers neuronal processes is lost through disease, neural stem cells recapitulate the developmental program of 'myelination'. The underlying molecular mechanisms often fail in the ageing brain.
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Nave, KA. An ageing view of myelin repair. Nature 455, 478–479 (2008). https://doi.org/10.1038/455478a
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DOI: https://doi.org/10.1038/455478a
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