How did organismal complexity evolve at a cellular level, and how does a genome encode it? The answer might lie in differences, not in the number of genes an organism has, but rather in the regulation of gene expression.
References
Putnam, N. H. et al. Science 317, 86–94 (2007).
Technau, U. et al. Trends Genet. 21, 633–639 (2005).
Grimson, A. et al. Nature 455, 1193–1197 (2008).
Bartel, D. P. Cell 116, 281–297 (2004).
Ambros, V. Nature 431, 350–355 (2004).
Pasquinelli, A. E. et al. Nature 408, 86–89 (2000).
Sempere, L. F., Cole, C. N., McPeek, M. A. & Peterson, K. J. J. Exp. Zool. B Mol. Dev. Evol. 306, 575–588 (2006).
Prochnik, S. E., Rokhsar, D. S. & Aboobaker, A. A. Dev. Genes Evol. 217, 73–77 (2007).
Srivastava, M. et al. Nature 454, 955–960 (2008).
Fu, X., Adamski, M. & Thompson, E. M. Mol. Biol. Evol. 25, 1067–1080 (2008).
Lu, J. et al. Nature Genet. 40, 351–355 (2008).
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Technau, U. Small regulatory RNAs pitch in. Nature 455, 1184–1185 (2008). https://doi.org/10.1038/4551184a
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DOI: https://doi.org/10.1038/4551184a
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