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Systems biology

Metabonomics

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Organisms often respond in complex and unpredictable ways to stimuli that cause disease or injury. By measuring and mathematically modelling changes in the levels of products of metabolism found in biological fluids and tissues, metabonomics offers fresh insight into the effects of diet, drugs and disease.

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Figure 1: Metabonomics of yore.

THE ROYAL LIBRARY, COPENHAGEN

Figure 2: The discovery process in metabonomics.
Figure 3: Applications of metabonomics.

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Authors and Affiliations

  1. Jeremy K. Nicholson and John C. Lindon are in the Department of Biomolecular Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK,

    Jeremy K. Nicholson & John C. Lindon

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  1. Jeremy K. Nicholson
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  2. John C. Lindon
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Nicholson, J., Lindon, J. Metabonomics. Nature 455, 1054–1056 (2008). https://doi.org/10.1038/4551054a

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