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Surprising side effects

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A drug that normally suppresses an immune response by trapping lymphocytes in lymphoid organs results in the elimination of a chronic viral infection when applied at low doses. Why should this be?

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Figure 1: Blocked lymphocyte recirculation.

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Authors and Affiliations

  1. Michael J. Bevan and Pamela J. Fink are in the Department of Immunology, University of Washington, Seattle, Washington 98195-7370, USA. mbevan@u.washington.edu pfink@u.washington.edu,

    Michael J. Bevan & Pamela J. Fink

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  1. Michael J. Bevan
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  2. Pamela J. Fink
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Bevan, M., Fink, P. Surprising side effects. Nature 454, 837–838 (2008). https://doi.org/10.1038/454837a

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