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Structural biology

Snapshots of DNA repair

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In recombinational DNA repair, nearly identical sequences in chromosomes are found and swapped. Structures of the RecA–DNA complexes involved provide insight into the mechanism and energetics of this universal process.

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Figure 1: DNA strand exchange promoted by RecA protein.

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Kowalczykowski, S. Snapshots of DNA repair. Nature 453, 463–465 (2008). https://doi.org/10.1038/453463a

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