In the fable of the tortoise and the hare, the reptilian slowcoach beats its fleet-footed rival in a race. A zinc catalyst recreates this story by giving a less reactive chemical group a turn of speed over a rival group.
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References
Ohshima, T., Iwasaki, T., Maegawa, Y., Yoshiyama, A. & Mashima, K. J. Am. Chem. Soc. 130, 2944–2945 (2008).
Gardossi, L., Bianchi, D. & Klibanov, A. M. J. Am. Chem. Soc. 113, 6328–6329 (1991).
Sharpless, K. B. & Michaelson, R. C. J. Am. Chem. Soc. 95, 6136–6137 (1973).
Janda, K. D. et al. Science 259, 490–493 (1993).
Lewis, C. A. & Miller, S. J. Angew. Chem. Int. Edn 45, 5616–5619 (2006).
Kharasch, M. S. & Tawney, P. O. J. Am. Chem. Soc. 63, 2308–2316 (1941).
Sontag, N. O. Chem. Rev. 52, 237–416 (1952).
Stanton, M. G. & Gagne, M. R. J. Am. Chem. Soc. 119, 5075–5076 (1997).
Hoerter, J. M. et al. J. Am. Chem. Soc. 128, 5177–5183 (2006).
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Peris, G., Miller, S. Triumph of a chemical underdog. Nature 452, 415–416 (2008). https://doi.org/10.1038/452415a
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DOI: https://doi.org/10.1038/452415a
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