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Indifferent chaperones

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How do nonspecific enzymes that help to correct RNA folding identify misfolded structures among similar, properly folded RNAs? It seems that careful discrimination has little to do with it.

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Figure 1: Schematic folding landscape of group-I intron RNAs.

References

  1. Herschlag, D. J. Biol. Chem. 270, 20871–20874 (1995).

    Article  CAS  Google Scholar 

  2. Schroeder, R., Barta, A. & Semrad, K. Nature Rev. Mol. Cell Biol. 5, 908–919 (2004).

    Article  CAS  Google Scholar 

  3. Bhaskaran, H. & Russell, R. Nature 449, 1014–1018 (2007).

    Article  ADS  CAS  Google Scholar 

  4. Linder, P. Nucleic Acids Res. 34, 4168–4180 (2006).

    Article  CAS  Google Scholar 

  5. Yang, Q. & Jankowsky, E. Nature Struct. Mol. Biol. 13, 981–986 (2006).

    Article  CAS  Google Scholar 

  6. Mohr, S., Stryker, J. M. & Lambowitz, A. M. Cell 109, 769–779 (2002).

    Article  CAS  Google Scholar 

  7. Tijerina, P., Bhaskaran, H. & Russell, R. Proc. Natl Acad. Sci. USA 103, 16698–16703 (2006).

    Article  ADS  CAS  Google Scholar 

  8. Yang, Q., Fairman, M. E. & Jankowsky, E. J. Mol. Biol. 368, 1087–1100 (2007).

    Article  CAS  Google Scholar 

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Jankowsky, E. Indifferent chaperones. Nature 449, 999–1000 (2007). https://doi.org/10.1038/449999a

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