Calcium ions act as signals between cells, but their exact locations — at the nanometre scale — have been difficult to pinpoint. The latest biosensor promises to reveal these details in dynamic living systems.
References
Tour, O. et al. Nature Chem. Biol. 3, 423–431 (2007).
Griffin, B. A., Adams, S. R. & Tsien, R. Y. Science 281, 269–272 (1998).
Hauser, C. T. & Tsien, R. Y. Proc. Natl Acad. Sci. USA 104, 3693–3697 (2007).
Ojida, A. et al. J. Am. Chem. Soc. 128, 10452–10459 (2006).
Prescher, J. A. & Bertozzi, C. R. Nature Chem. Biol. 1, 13–21 (2005).
Chen, I. & Ting, A. Y. Curr. Opin. Biotechnol. 16, 35–40 (2005).
Guignet, E. G., Hovius, R. & Vogel, H. Nature Biotechnol. 22, 440–444 (2004).
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Chang, C. Ions illuminated. Nature 448, 654–655 (2007). https://doi.org/10.1038/448654a
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DOI: https://doi.org/10.1038/448654a
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