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Chemical biology

A degrading solution to pollution

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Environmental pollutants such as dioxins affect human health. It now seems that dioxins exert their effect by forming atypical enzyme complexes that mediate the breakdown of steroid-hormone receptors.

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Figure 1: Dioxins and the degradation of the oestrogen receptor (ERα).

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Harper, J. A degrading solution to pollution. Nature 446, 499–500 (2007). https://doi.org/10.1038/446499a

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