Rubisco is said to be both the most important enzyme on Earth and surprisingly inefficient. Yet an understanding of the reaction by which it fixes CO2 suggests that evolution has made the best of a bad job.
References
Spreitzer, R. J. & Salvucci, M. E. Annu. Rev. Plant Biol. 53, 449–475 (2002).
Tcherkez, G. G. B., Farquhar, G. D. & Andrews, T. J. Proc. Natl Acad. Sci. USA 103, 7246–7251 (2006).
Parry, M. A. J., Andralojc, P. J., Mitchell, R. A. M., Madgwick, P. J. & Keys, A. J. J. Exp. Bot. 54, 1321–1333 (2003).
Whitney, S. M., von Caemmerer, S., Hudson, G. S. & Andrews, T. J. Plant Physiol. 121, 579–588 (1999).
Ashida, H., Danchin, A. & Yokota, A. Res. Microbiol. 156, 611–618 (2005).
Yoshizawa, Y., Toyoda, K., Arai, H., Ishii, M. & Igarashi, M. J. Bacteriol. 156, 5685–5691 (2004).
Giordano, M., Beardall, J. & Raven, J. A. Annu. Rev. Plant Biol. 56, 99–131 (2005).
Brown, N. J., Parsley, K. & Hibberd, J. M. Trends Plant Sci. 10, 215–221 (2005).
Dodd, A. N., Borland, A. M., Haslam, R. P., Griffiths, H. & Maxwell, C. J. Exp. Bot. 53, 565–580 (2002).
Parikh, M. H., Greene, D. N., Woods, K. K. & Matsumura, I. Protein Engng Design Select. 19, 113–119 (2006).
Long, S. P., Zhu, X.-G., Naidu, S. & Ort, D. R. Plant Cell Environ. 29, 315–330 (2006).
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Griffiths, H. Designs on Rubisco. Nature 441, 940–941 (2006). https://doi.org/10.1038/441940a
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DOI: https://doi.org/10.1038/441940a
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