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Metabolism

Bile acids heat things up

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Thyroid hormone causes fat loss, but harnessing this action to treat obesity is difficult because it is associated with harmful side effects. However, bile acids generate active thyroid hormone just where it is needed.

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Figure 1: Bile acids in energy homeostasis.

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Authors and Affiliations

  1. the Diabetes Center and Department of Medicine, University of California School of Medicine, S1212, 513 Parnassus Avenue, San Francisco, 94143-0540, California, USA

    John D. Baxter & Paul Webb

  2. John D. Baxter & Paul Webb

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  1. John D. Baxter
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  2. Paul Webb
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Baxter, J., Webb, P. Bile acids heat things up. Nature 439, 402–403 (2006). https://doi.org/10.1038/439402a

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