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Metabolism

A is for adipokine

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Adipokines are hormones that signal changes in fatty-tissue mass and energy status so as to control fuel usage. A fat-derived adipokine that binds to vitamin A provides a new link between obesity and insulin resistance.

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Figure 1: Retinol binding protein-4 (RBP4) in glucose metabolism.

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Authors and Affiliations

  1. the Departments of Pharmacology and Cancer Biology and of Medicine, Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, 27710, North Carolina, USA

    Deborah M. Muoio & Christopher B. Newgard

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  1. Deborah M. Muoio
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  2. Christopher B. Newgard
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Muoio, D., Newgard, C. A is for adipokine. Nature 436, 337–338 (2005). https://doi.org/10.1038/436337a

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