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Gene regulation

Expression and silencing coupled

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The RNA interference pathway can inhibit the expression of specific genes. It now seems that an essential component of the silencing process is the gene-expression machinery itself.

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Figure 1: Transcription-coupled RNA interference.

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Buratowski, S., Moazed, D. Expression and silencing coupled. Nature 435, 1174–1175 (2005). https://doi.org/10.1038/4351174b

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