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Ion pump in the movies

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Insight into how membrane ion pumps work requires structural snapshots of various stages of their catalytic cycle. Now a fifth freeze-frame image of a calcium pump in action adds to a striking body of work on this protein.

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Figure 1: The Post–Albers cycle: states of the ion pump Ca2+-ATPase as it transports Ca2+ ions into the sarcoplasmic reticulum.
Figure 2: Ca2+-ATPase in the five key states for which high-resolution structures are available.

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  1. Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Marie-Curie-Strasse 15, Frankfurt am Main, D-60439, Germany

    C. Roy D. Lancaster

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  1. C. Roy D. Lancaster
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Lancaster, C. Ion pump in the movies. Nature 432, 286–287 (2004). https://doi.org/10.1038/432286a

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