Histone proteins, which serve as scaffolds for packaging DNA, can be modified in numerous ways. It's been thought that one modification, methylation, is irreversible — but that view must now change.
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Zhang, Y. No exception to reversibility. Nature 431, 637–638 (2004). https://doi.org/10.1038/431637a
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DOI: https://doi.org/10.1038/431637a
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