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Theoretical immunology

Parasitic turncoat

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Some parasites evade the immune response of their victim by changing their antigenic coat. Surprisingly, it seems that the trick works best if the new coat isn't completely different from the old one.

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Figure 1: The merozoites of the malaria parasite, Plasmodium falciparum, erupt from an infected blood cell, and will carry the infection into other blood cells.

G. MURTI/SPL

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Antia, R., Koella, J. Parasitic turncoat. Nature 429, 511–513 (2004). https://doi.org/10.1038/429511a

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