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Ageing and the mystery at Arles

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What determines how long we will live? Studies of simple organisms, single cells and mammals hint that certain shared principles underlie ageing, and raise the possibility of devising ways to extend life — if we want to.

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Figure 1: Life and death of a worm.
Figure 2: The DAF-16 signalling pathway and lifespan.
Figure 3: A current version of the free-radical theory of ageing.

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Authors and Affiliations

  1. Cardiovascular Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Building 10/6N-240, 10 Center Drive, Bethesda, 20892-1622, Maryland, USA

    Shino Nemoto & Toren Finkel

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  1. Shino Nemoto
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  2. Toren Finkel
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Nemoto, S., Finkel, T. Ageing and the mystery at Arles. Nature 429, 149–152 (2004). https://doi.org/10.1038/429149a

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