Skip to main content

Advertisement

Log in

RNA finds a simpler way

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

Is there no end to the versatility of RNA? The latest feat to be revealed is RNA's ability to switch off genes through a neatly straightforward mechanism. So it isn't only proteins that can repress gene activity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Repression systems.

References

  1. Winkler, W. C., Nahvi, A., Roth, A., Collins, J. A. & Breaker, R. R. Nature 428, 281–286 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Doudna, J. A. & Cech, T. R. Nature 418, 222–228 (2002).

    Article  ADS  CAS  Google Scholar 

  3. Michel, F., Hanna, M., Green, R., Bartel, D. P. & Szostak, J. W. Nature 347, 578–580 (1989).

    Article  ADS  Google Scholar 

  4. Puglisi, J. D. et al. Science 257, 76–80 (1992).

    Article  ADS  CAS  Google Scholar 

  5. Ellington, A. D. & Szostak, J. W. Nature 346, 818–822 (1990).

    Article  ADS  CAS  Google Scholar 

  6. Gold, L., Polisky, B., Uhlenbeck, O. & Yarus, M. Annu. Rev. Biochem. 64, 763–797 (1995).

    Article  CAS  Google Scholar 

  7. Zimmermann, G. R., Jenison, R. D., Wick, C. L., Simorre, J. P. & Pardi, A. Nature Struct. Biol. 4, 644–649 (1997).

    Article  CAS  Google Scholar 

  8. Nahvi, A. et al. Chem. Biol. 9, 1043–1049 (2002).

    Article  CAS  Google Scholar 

  9. Mironov, A. S. et al. Cell 111, 747–756 (2002).

    Article  CAS  Google Scholar 

  10. Silverman, S. K. RNA 9, 377–383 (2003).

    Article  CAS  Google Scholar 

  11. Jacob, F. & Monod, J. J. Mol. Biol. 3, 318–356 (1961).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

R. Cech, T. RNA finds a simpler way. Nature 428, 263–264 (2004). https://doi.org/10.1038/428263a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/428263a

  • Springer Nature Limited

This article is cited by

Navigation