Artemisinins have been used since ancient times to treat malaria. A new theory could explain how this age-old medicine is able to cause the death of the malaria parasite.
This is a preview of subscription content, log in via an institution to check access.
References
Haynes, R. Curr. Opin. Infect. Dis. 14, 719–726 (2001).
Eckstein-Ludwig, U. et al. Nature 424, 957–961 (2003).
Greenwood, B. & Mutabingwa, T. Nature 415, 670–672 (2002).
Ridley, R. G. Nature 415, 686–693 (2002).
Meshnick, S. R., Taylor, T. E. & Kamchonwongpaisan, S. Microbiol. Rev. 60, 301–315 (1996).
Robert, A., Cazelles, J. & Meunier, B. Chem. Int. 40, 1954–1957 (2001).
Olliaro, P., Haynes, R. K., Meunier, B. & Yongyuth, Y. Trends Parasitol. 17, 123–126 (2001).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ridley, R. To kill a parasite. Nature 424, 887–889 (2003). https://doi.org/10.1038/424887a
Issue Date:
DOI: https://doi.org/10.1038/424887a
- Springer Nature Limited
This article is cited by
-
Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review
Parasites & Vectors (2018)
-
Arteether resistance reversal by ketoconazole/fluconazole in rodent malaria parasite Plasmodium vinckei
Parasitology Research (2015)
-
A plausible mechanism for the antimalarial activity of artemisinin: A computational approach
Scientific Reports (2013)
-
The function of terpene natural products in the natural world
Nature Chemical Biology (2007)