A sophisticated model of the effects of mutating the retinoblastoma gene reveals a window of opportunity in which cells can be released from the normal control of proliferation, before back-up mechanisms take effect.
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Berns, A. Timing will tell. Nature 424, 140–141 (2003). https://doi.org/10.1038/424140a
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DOI: https://doi.org/10.1038/424140a
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